Editorial: Navigating the microbial landscape: integrating mass spectrometry imaging and other multimodal imaging approaches for spatially resolved microbial studies [* Cross-Reference *]

Version 1.0
Michael D. Tuck; Maureen Feucherolles; Peter Verhaert, 2026, "Editorial: Navigating the microbial landscape: integrating mass spectrometry imaging and other multimodal imaging approaches for spatially resolved microbial studies [* Cross-Reference *]", https://lore.list.lu/citation?persistentId=perma:LIST.WW0G4P, LIST Open Repository, V1
Learn about Data Citation Standards.
Dataset Metrics
0 Downloads
Description
contributions that advance precisely this capacity, uniting mass spectrometry imaging (MSI) and complementary multimodal imaging approaches in service of spatially resolved microbial science.The four articles assembled here span the breadth of this emerging field, from foundational method development to clinical application. Situating these methodological and clinical advances within a broader biological framework, Meyers et al. provide a comprehensive review of the microbiome's role in cancer metastasis, surveying how specific bacterial taxa, including Fusobacterium nucleatum, Bacteroides fragilis, and Helicobacter pylori, may influence four key steps of the metastatic cascade through direct invasion, toxin secretion, and immune modulation. Critically, the review argues that resolving the microbiome's contribution to metastatic progression requires moving beyond compositional profiling toward spatially-resolved approaches. This includes MALDI-MSI, DESI-MSI, NanoSIMS, imaging mass cytometry, and spatial transcriptomics workflows that can map microbial communities, their metabolites, and their interactions with host cells directly within the tumor microenvironment.Taken together, these four contributions articulate a unifying conviction at the heart of this Research Topic: that the biology of microorganisms is inseparable from their spatial and molecular context, and that imaging technologies, specificically MSI and complementary multimodal imaging, are the instruments that make that context achievable. Whether the objective is to map a metabolite to a bacterial niche in the gut, to capture the metabolic signature of a pathogen in a living host cell, to identify an organism from a clinical isolate, or to chart the microbiome's influence across the stages of metastasis, each paper demonstrates that spatial resolution and molecular specificity are not technical luxuries but scientific necessities. This Research Topic reflects a broader shift in approaching the Biology of Microbes: from cataloguing the microbiome "who is present?", to understanding "where everybody is", "what they are doing", and, ultimately, "how microbial activities shape the biological systems and environment they inhabit". (2026-06-09)
***This entry has been automatically imported via OpenAlex by LIST harvest scripts. Please refer to https://doi.org/10.3389/fcimb.2026.1887183 for the original and latest version of the publication*** (2026-07-01)
Subject Chemistry; Medicine, Health and Life Sciences; Physics
Keyword Mass spectrometry imaging, Spatial contextual awareness, Phenomics, Context (archaeology), Workflow, Microbiome, Profiling (computer programming), Proteogenomics, Organism
License/Data Use Agreement

CC BY 4.0

There are no files in this dataset.
Edit File

This file has already been deleted (or replaced) in the current version. It may not be edited.

Restrict Access

Restricting limits access to published files. People who want to use the restricted files can request access by default. If you disable request access, you must add information about access to the Terms of Access field.

Learn about restricting files and dataset access in the User Guide.

Enable access request
You must enable request access or add terms of access to restrict file access.
Save Changes
Edit Embargo

The selected file or files have already been published. Contact an administrator to change the embargo date or reason of the file or files.
Edit Retention Period

The selected file or files have already been published. Contact an administrator to change the retention period date or reason of the file or files.
Delete Files

The file will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Select File(s)

Please select one or more files.

Share Dataset

Share this dataset on your favorite social media networks.

Continue
Dataset Citations

Citations for this dataset are retrieved from Crossref via DataCite using Make Data Count standards. For more information about dataset metrics, please refer to the User Guide.

Sorry, no citations were found.
Inaccessible Files Selected

The selected file(s) may not be downloaded because you have not been granted access or the file(s) have a retention period that has expired or the files can only be transferred via Globus.

You may request access to any restricted file(s) by clicking the Request Access button.

Ineligible Files Selected

The selected file(s) may not be transferred because you have not been granted access or the file(s) have a retention period that has expired or the files are not Globus accessible.

You may request access to any restricted file(s) by clicking the Request Access button.

Download Options

The files selected are too large to download as a ZIP.

You can select individual files that are below the 100.0 MB download limit from the files table, or use the Data Access API for programmatic access to the files.

Select File(s)

Please select a file or files to be downloaded.

Inaccessible Files Selected

The selected file(s) may not be downloaded because you have not been granted access or the file(s) have a retention period that has expired.

Click Continue to download the files you have access to download.

Ineligible Files Selected

Some file(s) cannot be transferred. (They are restricted, embargoed, with an expired retention period, or not Globus accessible.)

Click Continue to transfer the elligible files.

Delete Dataset

Are you sure you want to delete this dataset and all of its files? You cannot undelete this dataset.

Delete Draft Version

Are you sure you want to delete this draft version? Files will be reverted to the most recently published version. You cannot undelete this draft.

Unpublished Dataset Preview URL

Preview URL can only be used with unpublished versions of datasets.

Unpublished Dataset Preview URL

Are you sure you want to disable the Preview URL? If you have shared the Preview URL with others they will no longer be able to use it to access your unpublished dataset.

Delete Files

The file(s) will be deleted after you click on the Delete button.

Files will not be removed from previously published versions of the dataset.

Compute

This dataset contains restricted files you may not compute on because you have not been granted access.

Deaccession Dataset

Are you sure you want to deaccession? This is permanent and the selected version(s) will no longer be viewable by the public.

Deaccession Dataset

Are you sure you want to deaccession this dataset? This is permanent an it will no longer be viewable by the public.

Version Differences Details

Please select two versions to view the differences.

Version Differences Details
 
Version:
Last Updated:
Version:
Last Updated:
Select File(s)

Please select a file or files for access request.

Select File(s)

Embargoed files cannot be accessed. Please select an unembargoed file or files for your access request.

Edit Tags

Select existing file tags or create new tags to describe your files. Each file can have more than one tag.

Request Access

 You need to Log In to request access.

Dataset Terms

Please confirm and/or complete the information needed below in order to request access to files in this dataset.

This dataset is made available under the following terms. Please confirm and/or complete the information needed below in order to continue.

Our Community Norms as well as good scientific practices expect that proper credit is given via citation. Please use the data citation shown on the dataset page.

CC BY 4.0

Preview Guestbook

Upon downloading files the guestbook asks for the following information.

Account Information

Package File Download

Use the Download URL in a Wget command or a download manager to download this package file. Download via web browser is not recommended. User Guide - Downloading a Dataverse Package via URL

https://lore.list.lu/api/access/datafile/

Compute Batch
Clear Batch
Dataset Persistent Identifier Change Compute Batch
Compute Batch
Submit for Review

You will not be able to make changes to this dataset while it is in review.

Publish Dataset

Are you sure you want to republish this dataset?

Select if this is a minor or major version update.

Publish Dataset

This dataset cannot be published until LIST Open Repository is published by its administrator.

Return to Author

Return this dataset to contributor for modification. The reason for return entered below will be sent by email to the author.

Curation Status History
StatusDateAssigner
No records found.
Add/Edit a Version Note
Styled Citation