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Persistent Identifier
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perma:LIST.GXMCKA |
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Publication Date
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2026-07-06 |
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Title
| Poromechanical Modelling of the Time‐Dependent Response of In Vivo Human Skin During Extension [* Cross-Reference *] |
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Other Identifier
| https://doi.org/10.1002/cnm.70111
OpenAlex ID: https://openalex.org/W4416995409 |
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Author
| Thomas Lavigne (Centre National de la Recherche Scientifique, Université de Bordeaux, University of Luxembourg, Institut de Mécanique et d'Ingénierie de Bordeaux, Luxembourg Institute of Science and Technology, Luxembourg Institute of Socio-Economic Research, Institut de Biomécanique Humaine Georges Charpak, Institut Polytechnique de Bordeaux) - ORCID: https://orcid.org/0000-0002-3025-2423
Stéphane Urcun (University of Luxembourg, Luxembourg Institute of Science and Technology, Luxembourg Institute of Socio-Economic Research) - ORCID: https://orcid.org/0000-0002-5164-5904
Emmanuelle Jacquet (Centre National de la Recherche Scientifique, Franche-Comté Électronique Mécanique Thermique et Optique - Sciences et Technologies, Université Marie et Louis Pasteur) - ORCID: https://orcid.org/0000-0002-5573-5341
Jérôme Chambert (Centre National de la Recherche Scientifique, Franche-Comté Électronique Mécanique Thermique et Optique - Sciences et Technologies, Université Marie et Louis Pasteur) - ORCID: https://orcid.org/0000-0002-1713-0325
Aflah Elouneg (Centre National de la Recherche Scientifique, Franche-Comté Électronique Mécanique Thermique et Optique - Sciences et Technologies, Université Marie et Louis Pasteur) - ORCID: https://orcid.org/0000-0002-0814-6704
Camilo A. Suarez‐Afanador (University of Luxembourg, Luxembourg Institute of Science and Technology, Luxembourg Institute of Socio-Economic Research) - ORCID: https://orcid.org/0000-0002-8816-4848
Stéphane Bordas (University of Luxembourg, Luxembourg Institute of Science and Technology, Luxembourg Institute of Socio-Economic Research) - ORCID: https://orcid.org/0000-0001-8634-7002
Giuseppe Sciumè (Centre National de la Recherche Scientifique, Université de Bordeaux, Institut Universitaire de France, Institut de Mécanique et d'Ingénierie de Bordeaux, Institut Polytechnique de Bordeaux) - ORCID: https://orcid.org/0000-0001-5231-7374
Pierre‐Yves Rohan (Institut Universitaire de France, Institut de Biomécanique Humaine Georges Charpak) - ORCID: https://orcid.org/0000-0001-6171-7724 |
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Point of Contact
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LIST QDKM (LIST) |
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Description
| This paper proposes a proof of concept application of a biphasic constitutive model to identify the mechanical properties of in vivo human skin under extension. Although poromechanics theory has been extensively used to model other soft biological tissues, only a few studies have been published for skin, and most have been limited to ex vivo or in silico conditions. However, in vivo procedures are crucial to determine the subject-specific properties at different body sites. This study focuses on cyclic uni-axial extension of the upper arm skin, using unpublished data collected by Chambert et al. Our analysis shows that a two-layer finite element model allows representing all relevant features of the observed mechanical response to the imposed external loading, which was composed, in this contribution, of four loading-sustaining-unloading cycles. The Root Mean Square Error (RMSE) between the calibrated model and the measured Force-time response was (Formula presented.) N. Our biphasic model represents a preliminary step towards investigating the mechanical conditions responsible for the onset of injury. It allows for the analysis of changes in Interstitial Fluid (IF) pressure, flow, and osmotic pressure, in addition to the mechanical fields. Future work will focus on the interaction of multiple biochemical factors and the complex network of regulatory signals. (2025-12-01)
***This entry has been automatically imported via OpenAlex by LIST harvest scripts. Please refer to https://doi.org/10.1002/cnm.70111 for the original and latest version of the publication*** (2026-07-01) |
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Subject
| Engineering; Medicine, Health and Life Sciences; Physics |
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Keyword
| Extension (predicate logic)
In vivo
In silico
Finite element method
Ex vivo
Poromechanics
Human skin
Constitutive equation |
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Topic Classification
| Elasticity and Material Modeling
Thermoelastic and Magnetoelastic Phenomena
Tactile and Sensory Interactions |
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Deposit Date
| 2025-12-01 |
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Data Type
| Article |
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Data Source
| International Journal for Numerical Methods in Biomedical Engineering |